Gender differences in prepulse inhibition (PPI) in bipolar disorder: men have reduced PPI, women have increased PPI
نویسندگان
چکیده
منابع مشابه
Multivalent helix mimetics for PPI-inhibition.
The exploitation of multivalent ligands for the inhibition of protein-protein interactions has not yet been explored as a supramolecular design strategy. This is despite the fact that protein-protein interactions typically occur within the context of multi-protein complexes and frequently exploit avidity effects or co-operative binding interactions to achieve high affinity interactions. In this...
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Protein-Protein Interaction (PPI) networks contain valuable information for the isolation of groups of proteins that participate in the same biological function. Many proteins play different roles in the cell by taking part to several processes, but isolating the different processes in which a protein is involved is often a difficult task. In this paper we present a method based on a greedy loc...
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Cellular processes are typically carried out by protein complexes and functional modules. Identifying them plays an important role for our attempt to reveal principles of cellular organizations and functions. In this article, we review computational algorithms for identifying protein complexes and/or functional modules from protein-protein interaction (PPI) networks. We first describe issues an...
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Society is a registered educational charity (No. 1085494) and a company limited by guarantee (No. 04023541). Civitas is financed from a variety of private sources to avoid over-reliance on any single or small group of donors. All publications are independently refereed. All the Institute's publications seek to further its objective of promoting the advancement of learning. The views expressed a...
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on PPI therapy [3–7] , leading to the description of a new potential disease phenotype in the 2011 updated guidelines, i.e. PPI-responsive esophageal eosinophilia (PPIRee) [8] . Whether these patients represent a sub-phenotype of GERD, EoE or a combined mechanism of both disorders remains unknown. In the aforementioned reports neither histological specific features [6] , pH esophageal monitorin...
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ژورنال
عنوان ژورنال: The International Journal of Neuropsychopharmacology
سال: 2009
ISSN: 1461-1457,1469-5111
DOI: 10.1017/s1461145709000480